@article{oai:chuo-u.repo.nii.ac.jp:00001210,
 author = {櫻田, 伸一 and 木村, 友哉 and 小川, ゆかり and 有井, 秀和 and 北村, 裕介 and 芳賀, 正明 and 千喜良, 誠},
 journal = {中央大学理工学研究所論文集},
 month = {Mar},
 note = {application/pdf, Various fluorescent ruthenium and iridium aromatic amine complexes have been known to bind to double stranded DNA(ds-DNA) and utilization of the property for DNA-chip technology has long been attempted. Among various methods of detecting complexes bound specifically to ds-DNA, electrochemiluminescence (ECL) has attracted much attention as a technique that affords low price and high-speed detection method. In this study, we have synthesized ruthenium(II) and iridium(II) complexes of bpy (2, 2’-bipyridine), phen(1,10-phenanthroline), and ppy (2-phenylpyridine) respectively with large N-aromatic diimine intercalators and investigated the DNA binding affinity by spectroscopic methods and the ECL behaviors by DNA modified ECL electrode. The results indicated that Λ-[Ru(bpy)2(tpphz)]2+ (tpphz : tetrapyrido[3,2-a:2,3’-c:3”, 2”-h:2’’’,3’’’-j]-phenazine) has high affinity and selectivity for recognition of ds-DNA compared to the Δ-form complex and the other similar ruthenium complexes. It was also revealed that [Ir(ppy)2(tpphz)]+ recognized ds-DNA a little more efficiently than the ruthenium complexes though the affinity of the iridium complex to DNA was smaller than those of the ruthenium ones., 【査読有】},
 pages = {19--29},
 title = {ルテニウム(Ⅱ) およびイリジウム(Ⅲ) 錯体の電気化学発光によるDNA 二重らせんの検出},
 volume = {15},
 year = {2010},
 yomi = {サクラダ, シンイチ and キムラ, トモヤ and オガワ, ユカリ and アリイ, ヒデカズ and キタムラ, ユウスケ and ハガ, マサアキ and チキラ, マコト}
}